Biocrystallization test for early determination of oxidative stress

Authors: Cristina-Daniela Cîmpean1, Mihai Berteanu1,2


 1PhD Student, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

2Department of Rehabilitation Medicine, Elias University Hospital, Bucharest


Oxidative stress is an imbalance of oxidants/antioxidants in favor of oxidants as stated by Sies in 1985, and may arise due to excessive sports, physical and mental stress, high altitude exposure, diets, temperature variations, extreme cold or heat weather, smoking, hypoxia, immobilization stress and so on. It is also the main cause of the most common illnesses of the current age: cardiovascular disease, diabetes, infection, chronic fatigue syndrome, depression, malignancy, and neurodegenerative disorders. The early determination of oxidative stress, although important for health, is not always simple and often requires laborious and expensive analysis. Biocrystallization, also called sensitive crystallization, is a simple and inexpensive qualitative method used for almost 100 years in the study of herbs, foods and also in human health for orientation of diagnosis. The method also allows a rapid assessment of the therapeutic effectiveness of remedies or recommended procedures for patients with a certain pathology. In this paper we are looking to answer the following question: is it possible to use this method in order to assess the level of oxidative stress induced by varying environmental or internal factors and to observe the efficiency of the treatment?

Key words: biocrystallization, oxidative stress, carbonyl stress.