Authors: Ramona Jurcău1, Ioana Jurcău2
1 Department of Pathophysiology, Medicine Faculty, „Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania
2 Emergency Clinical Hospital for Children, Cluj-Napoca, Romania
Background. Citrus fruits are beneficial in the fight against all forms of stress, predominating antioxidative actions.
Aims. The objective was to highlight the relationship between citrus and stress, citrus and oxidative stress, in a short synthesis from the PubMed perspective publications.
Methods. To highlight the relationship between citrus and stress, several combinations of keywords were selected: Lemons+Stress (L+S), Orange+Stress (O+S), Grapefruit+Stress (G+S), Lemons+Oxidative Stress (L+OS), Orange+Oxidative Stress (O+OS), Grapefruit+Oxidative Stress (G+OS). PubMed analyzed filter was Species.
Results. The earliest publications were for L and the most recent for G. The most numerous publications were for O. Publications for S were more numerous than OS for all three selected Citrus fruits. Most studies were in humans for O+S and in animals for O+OS. The number of publications related to L+OS, O+OS, G+OS showed an increasing dynamic over time, both for N and for An and H, the highest number being in 2018.
Conclusions. 1) Interest in studies dealing with L+S/L+OS and O+S/O+OS was greater than research interest for G+S/G+OS. 2) Studies on the combination of citrus fruits and S were consistently more numerous, thus proving less interest in research related to L, O and G in relation to oxidative stress. 3) Publications for L, O and G, in combination with S and OS, although more numerous for animals, show that there is a growing interest in research involving human subjects. 4) The number of studies related to the three selected citrus fruits in combination with S and SO had an upward dynamic from the first publication until 2018, proving an increasing interest over time for these subjects.
Key words: citrus, stress, oxidative stress, PubMed.