Musculoskeletal involvement of SARS-CoV-2 infection with clinical implications

Authors: Laszlo Irsay1,2, Răzvan Iaz2, Florina Furtos2, Rodica Ungur1,2, Monica Borda1,2, Alina Ciubean1, Viorela Ciortea1,2



1 “Iuliu Hatieganu” University of Medicine and Pharmacy Cluj-Napoca, Department of Rehabilitation

2 Clinical Rehabilitation Hospital Cluj-Napoca, Romania



The COVID-19 pandemic is the deadliest disease of the modern medicine era. Internationally, governments are enforcing measures such as travel bans, quarantine, isolation, and social distancing leading to an extended period of time at home. This has resulted in reductions in physical activity and changes in dietary intakes that have the potential to accelerate sarcopenia, a deterioration of muscle mass and function (more likely in older populations), as well as increases in body fat. These changes in lifestyle, diseases including cardiovascular disease (CVD), diabetes, osteoporosis, frailty, cognitive decline, and depression have appeared much more frequently. Furthermore, CVD, diabetes, and elevated body fat are associated with greater risk of COVID-19 infection and more severe symptomology. The potential of low physical activity and isolation lead to an increased muscle loss and chronic disease.


Key words: SARS-CoV-2 infection, musculoskeletal rehabilitation, osteosarcopenia



Musculoskeletal involvement of SARS-CoV-2 infection with clinical implications